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Scientific Information on Uric Acid
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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Uric Acid
| Grade | Level of Evidence |
|---|---|
| A | Robust research conducted with repeated double blind clinical trials |
| B | Multiple studies where at least two are double-blind and placebo controlled |
| C | Single double blind study or multiple cohort studies |
| D | Uncontrolled or observational studies only |
| Level of Evidence | Supplement | Change | Magnitude of Effect Size | Scientific Consensus | Comments |
|---|---|---|---|---|---|
| C | Creatine | ![]() ![]() ![]() Minor | 100% See 2 studies | Minor reductions in uric acid. | |
| C | Ganoderma Lucidum | 100% See study | No changes in serum uric acid seem apparent | ||
| C | Gynostemma Pentaphyllum | 100% See study | No significant influences on uric acid | ||
| C | L-Carnitine | ![]() ![]() ![]() Minor | 100% See study | A decrease in uric acid has been noted | |
| C | Glutamine | ![]() ![]() ![]() Minor | 100% See study | An increase in serum urate has been noted in the range of 10-20% acutely, but attenuates with time and is likely not a concern within a week. Practical significance of... show | |
| D | Tetradecyl Thioacetic Acid | 100% See 2 studies | No significant alterations in serum uric acid seen with supplemental TTA | ||
| D | Hibiscus Sabdariffa | 100% See study | Does not appear to influence uric acid concentrations in serum |
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(Users who contributed to this page include KurtisFrank, Sol)