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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Testosterone
|Grade||Level of Evidence|
|A||Robust research conducted with repeated double blind clinical trials|
|B||Multiple studies where at least two are double-blind and placebo controlled|
|C||Single double blind study or multiple cohort studies|
|D||Uncontrolled or observational studies only|
|Level of Evidence ||Supplement||Change||Magnitude of Effect Size ||Scientific Consensus||Comments|
There appears to be an increase in testosterone following DHEA supplementation, but the vast majority of literature is in menopausal women (where testosterone contributes... show
Degree of testosterone spike is not overly notable, although it appears to be present
Although there is limited evidence to support an increase in testosterone, more evidence than not denies such an increase
There appears to be a time-dependent influence on testosterone, with acute doses of alcohol increasing testosterone secondary to creating energy influx in the liver (small... show
A very small (usually 12%) increase is noted in trained athletes consuming caffeine above 250mg prior to exercise, this may be dependent on exercise as studies without... show
No significant influences on testosterone in any tested demographic
Repeated trials have failed to find an increase in testosterone associated with velvet antler supplementation
No significant influence of acute usage on testosterone levels
An increase in testosterone has been noted in men with 3,332 IU of Vitamin D over the course of a year
No alterations in testosterone levels are noted with recommended doses of tribulus supplementation
Has failed to increase testosterone levels in one study.
May increase testosterone in infertile men, has also failed in fertile men to influence testosterone; likely a mere antioxidative effect in damaged testicles
No significant influence on testosterone levels
Notably effective in comparison to other testosterone boosting nutraceuticals, but still not overly potent.
See 2 studies
No significant influences on testosterone levels noted with magnesium intake
There appears to be a testosterone reduction associated with intake of licorice above 500mg, but the magnitude of this reduction is quite variable and there is no robust... show
Testosterone appears to be unaltered following ingestion of garcinia cambogia
Insufficient evidence to support changes in testosterone following 7-keto supplementation.
Was effective in infertile men, may not be effective in increasing testosterone in otherwise healthy men.
Increase of testosterone observed in men not overly potent and is highly variable.
A 23.5% increase has been noted in infertile men, it is not certain if this applies to fertile men.
No detectable influence on testosterone levels
Not the largest increase, and was in infertile men; may not apply to fertile men.
No alterations noted in serum testosterone associated with ecdysterone consumption
No detectable influence on testosterone levels in otherwise healthy men
No significant influence on testosterone levels following ingestion of Reishi
|C||Green Tea Catechins|
No significant influence on serum testosterone
No significant alterations noted
See 2 studies
An increase in testosterone is seen in infertile men. It is unsure if this increase in testosterone occurs in fertile and otherwise healthy men
A small increase in testosterone has been noted with 3g Royal Jelly for 6 months in older men and women, no studies in youth currently and practical significance of such... show
No significant alterations in testosterone noted
No detectable influence on testosterone levels in serum
No significant influence on testosterone noted with PS supplementation
No significant influence on circulating testosterone concentrations
There appears to be an interaction with Boron and testosterone in both genders, but it is seemingly unreliable
No significant influence on testosterone seen with yohimbine supplementation
|D||Eurycoma Longifolia Jack|
An increase has been noted in persons with hypogonadism, it is unsure if this applies to persons with normal testosterone levels
No significant influence on testosterone levels in men at risk for prostate cancer
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