Sperm Quality

   

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    Scientific Information on Sperm Quality

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    The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Sperm Quality
    GradeLevel of Evidence
    ARobust research conducted with repeated double blind clinical trials
    BMultiple studies where at least two are double-blind and placebo controlled
    CSingle double blind study or multiple cohort studies
    DUncontrolled or observational studies only
    Level of Evidence
    SupplementChange
    Magnitude of Effect Size
    Scientific ConsensusComments
    BL-Carnitine

    Notable

    Carnitine at 3g daily appears to increase sperm quality mostly related to sperm morphology; there are mixed effects on sperm motility

    BMucuna Pruriens

    Minor

    There appears to be an increase in seminal quality and oxidative parameters following 3-month ingestion of Mucuna pruriens, which is thought to be secondary to correcting... show

    CCoenzyme Q10

    Minor

    There may be some beneficial influences on the sperm quality, but they have not been reliably reported

    CAshwagandha

    Minor

    Appears to enhance seminal quality, needs more studies against comparators

    CShilajit

    Minor

    Sperm quality (and thought to apply to fertiliy) has been improved with Shilajit supplementation

    DD-Aspartic Acid

    Minor

    Appears effective, needs to be compared against a comparator.

    References

    1. Shukla KK, et al. Mucuna pruriens improves male fertility by its action on the hypothalamus-pituitary-gonadal axis. Fertil Steril. (2009)
    2. Katzenschlager R, et al. Mucuna pruriens in Parkinson's disease: a double blind clinical and pharmacological study. J Neurol Neurosurg Psychiatry. (2004)
    3. Nagashayana N, et al. Association of L-DOPA with recovery following Ayurveda medication in Parkinson's disease. J Neurol Sci. (2000)
    4. No authors listed. An alternative medicine treatment for Parkinson's disease: results of a multicenter clinical trial. HP-200 in Parkinson's Disease Study Group. J Altern Complement Med. (1995)
    5. Shukla KK, et al. Mucuna pruriens Reduces Stress and Improves the Quality of Semen in Infertile Men. Evid Based Complement Alternat Med. (2010)
    6. Gupta A, et al. A proton NMR study of the effect of Mucuna pruriens on seminal plasma metabolites of infertile males. J Pharm Biomed Anal. (2011)

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