Metabolic Rate

The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Metabolic Rate

Level of Evidence	Supplement	Change	Magnitude of Effect Size	Scientific Consensus	Comments
B	Ephedrine		Notable	100% See all 6 studies	Ephedrine, secondary to the stimulatory properties, appears to reliably increased metabolic rate
B	Green Tea Catechins			100% See all 3 studies	No significant influences on metabolic rate overall
B	Conjugated Linoleic Acid			60% See all 5 studies	Currently thought to be somewhat ineffective as the evidence supporting an increase are confounded with food intake whereas the evidence supporting no increase is more... show statistically robust.
C	L-Carnitine			100% See study	No significant influence on metabolic rate noted with carnitine supplementation
C	ECA		Notable	100% See 2 studies	The increase in metabolic rate seen with ephedrine is augmented with the inclusion of both aspirin and caffeine, hence its notable efficacy
C	Coconut Oil		Minor	50% See all 8 studies	Appears to be a short lived and of small magnitude increase in metabolic rate.
C	7-Keto DHEA		Notable	100% See study	Somewhat notable as the decrease seen with dieting was effectively abolished and reversed with 7-keto supplementation over 7 days of low caloric intake, but more evidence... show is required to establish the reliability of this and how strong it actually is.
C	Aframomum melegueta		Minor	100% See study	Requires more evidence, and the increase in metabolic rate was wholly conditional on cold therapy also being used (where supplementation with aframomum melegueta increased... show cold therapy's efficacy rather than per se increasing metabolic rate)
C	Caffeine		Minor	50% See 2 studies	Mixed effects on metabolic rate following acute doses of caffeine
C	Yerba Mate			100% See study	No significant influence on metabolic rate has been noted
C	Resveratrol		Minor	100% See study	A decrease in the metabolic rate has been noted in humans, thought to be related to the caloric restriction mimetic aspect
C	Fucoxanthin		Notable	100% See study	The lone study in obese premenopausal women noted a fairly remarkable increase in metabolic rate (the highest estimate being around 450kcal daily); this study requires... show replication to see if the effect size persists
C	Vitamin D			100% See study	No detectable influence on metabolic rate over time
C	Quercetin			100% See study	No significant influence on metabolic rate following acute Quercetin supplementation
D	Ginger			100% See study	Despite an increase in the thermic effect of food, overall metabolic rate does not appear affected
D	Fish Oil			100% See study	No significant influence on metabolic rate seen with fish oil supplementation
D	Sodium Bicarbonate		Minor	100% See study	An increase in metabolic rate has been noted and calculated (extrapolated) to be approximately 0.5% extra over the course of 24 hours, associated with a low dose of sodium... show bicarbonate (17mg/kg)

References

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(Common phrases used by users for this page include metabolic rate information, depth summary of metabolic)

(Users who contributed to this page include KurtisFrank, magnusson, Skip)