Kidney function

Scientific Information on Kidney function

Looking to buy Curcumin? Buy from Amazon.com

Follow this Page for updates

The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Kidney function

Level of Evidence	Supplement	Change	Magnitude of Effect Size	Scientific Consensus	Comments
B	Creatine			100% See all 10 studies	Appears to be unable to influence kidney function according to the trials conducted.
C	Benfotiamine			100% See study	Insufficient evidence to support enhanced kidney function.
C	Curcumin		Minor	100% See 2 studies	Appears to promote kidney function in instances where function is normally hindered
D	Astragalus Membranaceus		Notable	100% See study	Despite statistically weak evidence, case studies suggest curative effects. Potential of astragalus for aiding kidney function.
D	Conjugated Linoleic Acid			100% See study	No significant influence of CLA supplementation on renal functioning

References

1. Baum L, et al. Curcumin effects on blood lipid profile in a 6-month human study. Pharmacol Res. (2007)
2. Kuptniratsaikul V, et al. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis. J Altern Complement Med. (2009)
3. Wickenberg J, Ingemansson SL, Hlebowicz J. Effects of Curcuma longa (turmeric) on postprandial plasma glucose and insulin in healthy subjects. Nutr J. (2010)
4. Appendino G, et al. Potential role of curcumin phytosome (Meriva) in controlling the evolution of diabetic microangiopathy. A pilot study. Panminerva Med. (2011)
5. Chainani-Wu N, et al. High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus. J Am Acad Dermatol. (2012)
6. Pungcharoenkul K, Thongnopnua P. Effect of different curcuminoid supplement dosages on total in vivo antioxidant capacity and cholesterol levels of healthy human subjects. Phytother Res. (2011)
7. Agarwal KA, et al. Efficacy of turmeric (curcumin) in pain and postoperative fatigue after laparoscopic cholecystectomy: a double-blind, randomized placebo-controlled study. Surg Endosc. (2011)
8. Belcaro G, et al. Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Altern Med Rev. (2010)
9. Belcaro G, et al. Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis. Panminerva Med. (2010)
10. Ide H, et al. Combined inhibitory effects of soy isoflavones and curcumin on the production of prostate-specific antigen. Prostate. (2010)
11. Koosirirat C, et al. Investigation of the anti-inflammatory effect of Curcuma longa in Helicobacter pylori-infected patients. Int Immunopharmacol. (2010)
12. Kalpravidh RW, et al. Improvement in oxidative stress and antioxidant parameters in beta-thalassemia/Hb E patients treated with curcuminoids. Clin Biochem. (2010)
13. Alwi I, et al. The effect of curcumin on lipid level in patients with acute coronary syndrome. Acta Med Indones. (2008)
14. Baum L, et al. Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease. J Clin Psychopharmacol. (2008)
15. Biswas J, et al. Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal. Hum Exp Toxicol. (2010)
16. Durgaprasad S, et al. A pilot study of the antioxidant effect of curcumin in tropical pancreatitis. Indian J Med Res. (2005)
17. Hanai H, et al. Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial. Clin Gastroenterol Hepatol. (2006)
18. Holt PR, Katz S, Kirshoff R. Curcumin therapy in inflammatory bowel disease: a pilot study. Dig Dis Sci. (2005)
19. Khajehdehi P, et al. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. J Ren Nutr. (2012)
20. Khajehdehi P, et al. Oral supplementation of turmeric attenuates proteinuria, transforming growth factor-β and interleukin-8 levels in patients with overt type 2 diabetic nephropathy: a randomized, double-blind and placebo-controlled study. Scand J Urol Nephrol. (2011)
21. Carroll RE, et al. Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia. Cancer Prev Res (Phila). (2011)
22. He ZY, et al. Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin. Cancer Invest. (2011)
23. Shimouchi A, et al. Effect of dietary turmeric on breath hydrogen. Dig Dis Sci. (2009)
24. Usharani P, et al. Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study. Drugs R D. (2008)
25. Tuntipopipat S, et al. Chili, but not turmeric, inhibits iron absorption in young women from an iron-fortified composite meal. J Nutr. (2006)

(Common phrases used by users for this page include the kidneys functions scientific, neves-jr et al. appl physiol nutr metabol, kidneys function indepth, 13711441, 13710774)

(Users who contributed to this page include KurtisFrank, herman_gill, Sol)