Not inherently good or bad, Inflammation is the process recruiting immune cells to tissues in the body for their actions; good for immunity and cell defense, excessive levels can cause joint pain and accelerate signs of aging and disease pathology such as cancer or obesity.

This page features 3 unique references to scientific papers.

The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Inflammation
GradeLevel of Evidence
ARobust research conducted with repeated double blind clinical trials
BMultiple studies where at least two are double-blind and placebo controlled
CSingle double blind study or multiple cohort studies
DUncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific ConsensusComments
AFish Oil
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
BCoenzyme Q10
BVitamin C
BConjugated Linoleic Acid
CWhey Protein
CAlpha-Lipoic Acid
COlive leaf extract
CStinging Nettle
CSalvia hispanica
CJapanese Knotweed
CPanax ginseng
CVitamin D
CSea Buckthorn
DHibiscus sabdariffa


  1. Byleveld PM, et al. Fish oil feeding delays influenza virus clearance and impairs production of interferon-gamma and virus-specific immunoglobulin A in the lungs of mice. J Nutr. (1999)
  2. Schwerbrock NM, et al. Fish oil-fed mice have impaired resistance to influenza infection. J Nutr. (2009)
  3. Byleveld M, et al. Fish oil feeding enhances lymphocyte proliferation but impairs virus-specific T lymphocyte cytotoxicity in mice following challenge with influenza virus. Clin Exp Immunol. (2000)
  4. Herrera-Arellano A, et al. Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension: a controlled and randomized clinical trial. Phytomedicine. (2004)
  5. McKay DL, et al. Hibiscus sabdariffa L. tea (tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. J Nutr. (2010)
  6. Hernández-Pérez F, Herrera-Arellano A. Therapeutic use Hibiscus sabadariffa extract in the treatment of hypercholesterolemia. A randomized clinical trial. Rev Med Inst Mex Seguro Soc. (2011)
  7. Kuriyan R, et al. An evaluation of the hypolipidemic effect of an extract of Hibiscus Sabdariffa leaves in hyperlipidemic Indians: a double blind, placebo controlled trial. BMC Complement Altern Med. (2010)
  8. Haji Faraji M, Haji Tarkhani A. The effect of sour tea (Hibiscus sabdariffa) on essential hypertension. J Ethnopharmacol. (1999)
  9. Frank T, et al. Consumption of Hibiscus sabdariffa L. aqueous extract and its impact on systemic antioxidant potential in healthy subjects. J Sci Food Agric. (2012)
  10. Gurrola-Díaz CM, et al. Effects of Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy). Phytomedicine. (2010)
  11. Beltrán-Debón R, et al. The aqueous extract of Hibiscus sabdariffa calices modulates the production of monocyte chemoattractant protein-1 in humans. Phytomedicine. (2010)
  12. Mozaffari-Khosravi H, et al. Effects of sour tea (Hibiscus sabdariffa) on lipid profile and lipoproteins in patients with type II diabetes. J Altern Complement Med. (2009)
  13. Mozaffari-Khosravi H, et al. The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes. J Hum Hypertens. (2009)
  14. Herrera-Arellano A, et al. Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension. A randomized, double-blind, lisinopril-controlled clinical trial. Planta Med. (2007)

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