Insulin-like growth factor-1 (IGF-1) is an anabolic derivative of Growth Hormone that is thought to mediate cell growth and muscle protein synthesis. Supplements that increase IGF-1 are thought to promote muscle hypertrophy.

This page features 1 unique references to scientific papers.

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Also Known As

Insulin-like growth factor-1

The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what supplements affect IGF-1
Grade Level of Evidence
A Robust research conducted with repeated double blind clinical trials
B Multiple studies where at least two are double-blind and placebo controlled
C Single double blind study or multiple cohort studies
D Uncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific Consensus Comments
B Dehydroepiandrosterone
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
B Zinc
B Colostrum
B Creatine
B Red Clover Extract
C Trimethylglycine
C Ursolic Acid
C Citrulline
C Eurycoma Longifolia Jack
C L-Carnitine
C Melatonin
C Olive leaf extract
C Velvet Antler
C Whey Protein


  1. Bang HS1, et al Ursolic Acid-induced elevation of serum irisin augments muscle strength during resistance training in men . Korean J Physiol Pharmacol. (2014)

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