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About Dr. Yoni Freedhoff

Yoni Freedhoff, MD, is an assistant professor of family medicine at the University of Ottawa, where he’s the founder and medical director of the Bariatric Medical Institute. Dr. Freedhoff is considered to be Canada’s most outspoken obesity expert, and is the author of "The Diet Fix," a #1 national Canadian bestseller.

    In Progress

    This page on Hypertrophy is currently marked as in-progress. We are still compiling research.

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    Scientific Information on Hypertrophy

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    The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Hypertrophy
    GradeLevel of Evidence
    ARobust research conducted with repeated double blind clinical trials
    BMultiple studies where at least two are double-blind and placebo controlled
    CSingle double blind study or multiple cohort studies
    DUncontrolled or observational studies only
    Level of Evidence
    Magnitude of Effect Size
    Scientific ConsensusComments
    Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

    All information is still available and viewable on their respective supplement page.


    1. Jiang GL, et al. Randomized, double-blind, and placebo-controlled trial of clenbuterol in denervated muscle atrophy. ISRN Pharm. (2011)
    2. Kamalakkannan G, et al. Clenbuterol increases lean muscle mass but not endurance in patients with chronic heart failure. J Heart Lung Transplant. (2008)
    3. Maltin CA, et al. Clenbuterol, a beta-adrenoceptor agonist, increases relative muscle strength in orthopaedic patients. Clin Sci (Lond). (1993)

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