Functionality in Elderly or Injured

Supplements that improve symptoms of osteoarthritis, reduce the risk of falls, or improve muscle function in elderly persons tend to improve physical function and movement resulting in increased quality of life.


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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Functionality in Elderly or Injured
GradeLevel of Evidence
ARobust research conducted with repeated double blind clinical trials
BMultiple studies where at least two are double-blind and placebo controlled
CSingle double blind study or multiple cohort studies
DUncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific ConsensusComments
BS-Adenosyl Methionine
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
CKaempferia parviflora
CVitamin D
CKrill Oil
DCissus quadrangularis


  1. Panpimanmas S, et al. Experimental comparative study of the efficacy and side effects of Cissus quadrangularis L. (Vitaceae) to Daflon (Servier) and placebo in the treatment of acute hemorrhoids. J Med Assoc Thai. (2010)
  2. Oben JE, et al. The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids Health Dis. (2008)
  3. Oben J, et al. The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids Health Dis. (2006)
  4. Oben JE, et al. The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress. Lipids Health Dis. (2007)
  5. Singh V, et al. Clinical evaluation of cissus quadrangularis and moringa oleifera and osteoseal as osteogenic agents in mandibular fracture. Natl J Maxillofac Surg. (2011)
  6. Bloomer RJ, et al. Cissus quadrangularis reduces joint pain in exercise-trained men: A pilot study. Phys Sportsmed. (2013)

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