Functionality in Elderly or Injured

   

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    Scientific Information on Functionality in Elderly or Injured

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    The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Functionality in Elderly or Injured
    GradeLevel of Evidence
    ARobust research conducted with repeated double blind clinical trials
    BMultiple studies where at least two are double-blind and placebo controlled
    CSingle double blind study or multiple cohort studies
    DUncontrolled or observational studies only
    Level of Evidence
    SupplementChange
    Magnitude of Effect Size
    Scientific ConsensusComments
    BDehydroepiandrosterone

    Most evidence measuring functionality in elderly persons have not found any improvement with DHEA supplementation, although it is possible that DHEA may play a role

    BS-Adenosyl Methionine

    Minor

    Somewhat of an increase in functionality of elderly persons, most likely secondary to the beneficial effects on joint health.

    CCreatine

    Minor

    Possibly an effect, but the less reliable effects of creatine in the older population (which seem to respond less) seems to manifest here.

    CNitrate

    No significant influence has been noted on functional tests in elderly persons given nitrate supplementation

    CKaempferia Parviflora

    Minor

    Grip strength has been found to be increased in elderly persons associated with supplementation at low doses

    CVitamin D

    Notable

    An improvement in muscular and neural functionality in the elderly is thought to underlie the reductions of fall risk and reduced bone fracture rate seen in elderly cohorts

    CKrill Oil

    Minor

    The increase in functionality appears to be secondary to reductions in symptoms of rheumatoid arthritis

    DVinpocetine

    Minor

    An improvement in balance has been noted with vinpocetine ingestion in the elderly, which may be related to the attenuation of cognitive decline

    References

    1. Ulven SM, et al. Metabolic effects of krill oil are essentially similar to those of fish oil but at lower dose of EPA and DHA, in healthy volunteers. Lipids. (2011)
    2. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev. (2004)
    3. Banni S, et al. Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. Nutr Metab (Lond). (2011)
    4. Deutsch L. Evaluation of the effect of Neptune Krill Oil on chronic inflammation and arthritic symptoms. J Am Coll Nutr. (2007)
    5. Sampalis F, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev. (2003)

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