Fatigue Resistance

Fatigue Resistance tends to refer to the resiliance of the body towards developing fatigue (a sort of preeminative anti-fatigue effect), and supplements that enhance fatigue resistance are thought to be anti-stress and adaptogenic.

This page features 7 unique references to scientific papers.

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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what supplements affect Fatigue Resistance
Grade Level of Evidence
A Robust research conducted with repeated double blind clinical trials
B Multiple studies where at least two are double-blind and placebo controlled
C Single double blind study or multiple cohort studies
D Uncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific Consensus Comments
B Creatine
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
C Eleutherococcus senticosus
C Astaxanthin


  1. Comparison of the Addition of Siberian Ginseng (Acanthopanax senticosus) Versus Fluoxetine to Lithium for the Treatment of Bipolar Disorder in Adolescents: A Randomized, Double-Blind Trial
  2. Lee YJ, et al The effects of A. senticosus supplementation on serum lipid profiles, biomarkers of oxidative stress, and lymphocyte DNA damage in postmenopausal women . Biochem Biophys Res Commun. (2008)
  3. Kuo J, et al The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human . Chin J Physiol. (2010)
  4. Szołomicki J, et al The influence of active components of Eleutherococcus senticosus on cellular defence and physical fitness in man . Phytother Res. (2000)
  5. Bohn B, Nebe CT, Birr C Flow-cytometric studies with eleutherococcus senticosus extract as an immunomodulatory agent . Arzneimittelforschung. (1987)
  6. Asano K, et al Effect of Eleutherococcus senticosus extract on human physical working capacity . Planta Med. (1986)
  7. Cicero AF, et al Effects of Siberian ginseng (Eleutherococcus senticosus maxim.) on elderly quality of life: a randomized clinical trial . Arch Gerontol Geriatr Suppl. (2004)

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