Fatigue Resistance

Fatigue Resistance tends to refer to the resiliance of the body towards developing fatigue (a sort of preeminative anti-fatigue effect), and supplements that enhance fatigue resistance are thought to be anti-stress and adaptogenic.


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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Fatigue Resistance
GradeLevel of Evidence
ARobust research conducted with repeated double blind clinical trials
BMultiple studies where at least two are double-blind and placebo controlled
CSingle double blind study or multiple cohort studies
DUncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific ConsensusComments
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
CEleutherococcus senticosus


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  2. Djordjevic B, et al. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players. J Sports Med Phys Fitness. (2012)
  3. Saito M, et al. Astaxanthin increases choroidal blood flow velocity. Graefes Arch Clin Exp Ophthalmol. (2012)
  4. Miyawaki H, et al. Effects of astaxanthin on human blood rheology. J Clin Biochem Nutr. (2008)
  5. Comhaire FH, et al. Combined conventional/antioxidant "Astaxanthin" treatment for male infertility: a double blind, randomized trial. Asian J Androl. (2005)
  6. Earnest CP, et al. Effect of astaxanthin on cycling time trial performance. Int J Sports Med. (2011)
  7. Miyazawa T, et al. Erythrocytes carotenoids after astaxanthin supplementation in middle-aged and senior Japanese subjects. J Oleo Sci. (2011)
  8. Nakagawa K, et al. Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes. Br J Nutr. (2011)
  9. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. (2011)
  10. Choi HD, et al. Effects of astaxanthin on oxidative stress in overweight and obese adults. Phytother Res. (2011)
  11. Yoshida H, et al. Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia. Atherosclerosis. (2010)

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