Erections

   

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    Scientific Information on Erections

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    The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Erections
    GradeLevel of Evidence
    ARobust research conducted with repeated double blind clinical trials
    BMultiple studies where at least two are double-blind and placebo controlled
    CSingle double blind study or multiple cohort studies
    DUncontrolled or observational studies only
    Level of Evidence
    SupplementChange
    Magnitude of Effect Size
    Scientific ConsensusComments
    BYohimbine

    Minor

    Erections are increased following yohimbine ingestion which is thought to be a combination of alpha-2-adrenergic antagonism (enhancing relaxation of the penile tissue so... show

    BPanax Ginseng

    Minor

    An improvement in erectile dysfunction is seen with 3g of Korean Red Ginseng (fermented panax ginseng, regular panax ginseng not as well tested) which is thought to be... show

    CButea Superba

    Currently assumed to be ineffective for erections or erectile dysfunction due to the poor quality of the evidence in existence.

    CAshwagandha

    Unable to aid psychogenic erectile dysfunction more than placebo

    CCoenzyme Q10

    Minor

    Increased erectile function has been noted with CoQ10, but this may be secondary to reductions in symptoms of Peyronie's Disease

    CMaca

    Minor

    An increase in erection frequency has been noted in men, likely related to the libido enhancing properties

    CDehydroepiandrosterone

    No significant influence on erectile properties in persons with sexual dysfunction

    DL-Carnitine

    Minor

    One study has noted an improvement in erections in persons thought to have impaired blood flow

    DPycnogenol

    Minor

    May be proerectile in persons with organic erectile dysfunction (due to poor blood flow)

    DCitrulline

    Minor

    Hardness of erections in persons with mild erectile dysfunction appears to be increased following supplementation of citrulline supplementation.

    References

    1. Sureda A, et al. L-citrulline-malate influence over branched chain amino acid utilization during exercise. Eur J Appl Physiol. (2010)
    2. Thibault R, et al. Oral citrulline does not affect whole body protein metabolism in healthy human volunteers: results of a prospective, randomized, double-blind, cross-over study. Clin Nutr. (2011)
    3. Moinard C, et al. Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic study. Br J Nutr. (2008)
    4. Bendahan D, et al. Citrulline/malate promotes aerobic energy production in human exercising muscle. Br J Sports Med. (2002)
    5. Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res. (2010)
    6. Cormio L, et al. Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction. Urology. (2011)
    7. Orozco-Gutiérrez JJ, et al. Effect of L-arginine or L-citrulline oral supplementation on blood pressure and right ventricular function in heart failure patients with preserved ejection fraction. Cardiol J. (2010)
    8. Hickner RC, et al. L-citrulline reduces time to exhaustion and insulin response to a graded exercise test. Med Sci Sports Exerc. (2006)
    9. Sureda A, et al. Effects of L-citrulline oral supplementation on polymorphonuclear neutrophils oxidative burst and nitric oxide production after exercise. Free Radic Res. (2009)
    10. Ochiai M, et al. Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men. Int J Cardiol. (2012)
    11. Figueroa A, et al. Oral L-citrulline supplementation attenuates blood pressure response to cold pressor test in young men. Am J Hypertens. (2010)

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