This page on DNA methylation is currently marked as in-progress. We are still compiling research.
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Scientific Information on DNA methylation
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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect DNA methylation
| Grade | Level of Evidence |
|---|---|
| A | Robust research conducted with repeated double blind clinical trials |
| B | Multiple studies where at least two are double-blind and placebo controlled |
| C | Single double blind study or multiple cohort studies |
| D | Uncontrolled or observational studies only |
| Level of Evidence | Supplement | Change | Magnitude of Effect Size | Scientific Consensus | Comments |
|---|---|---|---|---|---|
| C | Creatine |   Minor | 100% See study | Lack of comparator prevents proper assessment of potency; practical relevance unknown | |
| C | Resveratrol | Minor | 100% See study | A decrease in DNA methylation rates has been noted |
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