Cortisol is the hormone that mediates waking up and a variety of catabolic (tissue breakdown) reactions; it isn't bad in any way, but many people with elevated cortisol could suffer pathology from it. In these scenarios, it is nice to lower cortisol and supplementation may be effective.

This page features 19 unique references to scientific papers.

The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Cortisol
GradeLevel of Evidence
ARobust research conducted with repeated double blind clinical trials
BMultiple studies where at least two are double-blind and placebo controlled
CSingle double blind study or multiple cohort studies
DUncontrolled or observational studies only
Level of Evidence
Magnitude of Effect Size
Scientific ConsensusComments
BFish Oil
Comparative Health Goals evidence only available to buyers of our Supplement-Goals Reference

All information is still available and viewable on their respective supplement page.
BVitamin C
CGamma Oryzanol
CMucuna pruriens
CSoy lecithin
CSchisandra chinensis
CSalvia sclarea
CRose Essential Oil
CBranched Chain Amino Acids
CArachidonic acid
CEurycoma Longifolia Jack
CGinkgo biloba
CVitamin E
CCocoa Extract
DNigella sativa
DVitamin B6
DVitamin B3


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