This page on Bone Mineral Density is currently marked as in-progress. We are still compiling research.
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Scientific Information on Bone Mineral Density
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The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect Bone Mineral Density
| Grade | Level of Evidence |
|---|---|
| A | Robust research conducted with repeated double blind clinical trials |
| B | Multiple studies where at least two are double-blind and placebo controlled |
| C | Single double blind study or multiple cohort studies |
| D | Uncontrolled or observational studies only |
| Level of Evidence | Supplement | Change | Magnitude of Effect Size | Scientific Consensus | Comments |
|---|---|---|---|---|---|
| B | Dehydroepiandrosterone | Most evidence suggests no increase in bone mineral density, but this may be due to short trials (6 months). Longer trials note a small but unreliable increase in bone mineral... show | |||
| C | Creatine |   Minor | 100% See study | Limited evidence in favor of improvements in bone mineral density with creatine supplementation | |
| C | Vitamin C | Minor | 100% See 2 studies | The rate of bone mineral density loss over time in elder women appears to be reduced with dietary antioxidants, and as such applies to Vitamin C supplementation. The protective... show | |
| C | Conjugated Linoleic Acid | 100% See study | No evidence to support a link between CLA and alterations in bone mineral density | ||
| C | Whey Protein | 100% See 2 studies | Currently no demonstrated benefit to bone mineral density, although protein in general appears to have a protective effect | ||
| C | Magnesium | Minor | 100% See study | An increase in bone mineral density has been noted with magnesium supplementation | |
| C | Coleus Forskohlii | Notable | 100% See study | Definitely requires more evidence, but a DXA confirmed increase in bone mass in men over 12 weeks makes this notable (rather than an increase in bone mass in osteoporotic... show | |
| C | Horny Goat Weed | Minor | 100% See study | The rate of bone loss over 2 years has been noted to be reduced with icariin supplementation, although not to a remarkable degree | |
| C | HMB | 100% See 2 studies | Studies that assess bone mineral density via DEXA, albeit short in duration and in athletes rather than populations at risk for osteoporosis, fail to find significant alterations... show | ||
| C | Leucic Acid | 100% See study | No significant alterations in bone mineral density | ||
| D | Yerba Mate | An association has been noted with increased bone mineral density and Mate consumption; insufficient evidence to suggest a causative role | |||
| D | Black Cohosh | 100% See study | No significant influence on bone mineral density | ||
| D | Fish Oil | 100% See study | No significant influence on bone mineral density noted with fish oil supplementation |
(Users who contributed to this page include KurtisFrank)
