ADHD in Children

   

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    Scientific Information on ADHD in Children

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    The Human Effect Matrix looks at human studies (excluding animal/petri-dish studies) to tell you what what supplements affect ADHD in Children
    GradeLevel of Evidence
    ARobust research conducted with repeated double blind clinical trials
    BMultiple studies where at least two are double-blind and placebo controlled
    CSingle double blind study or multiple cohort studies
    DUncontrolled or observational studies only
    Level of Evidence
    SupplementChange
    Magnitude of Effect Size
    Scientific ConsensusComments
    AFish Oil

    Minor

    Supplemental DHA above 300mg appears to be effective in reducing ADHD symptoms in children when supplemented

    CL-Carnitine

    Minor

    At least one study has noted reduction in ADHD symptoms in children

    CPhosphatidylserine

    Minor

    There appears to be reduced symptoms of both hyperactivity and attention deficit in children given PS, which may be more effective when the PS is complexed with fish oils

    References

    1. Hirayama S, et al. The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial. J Hum Nutr Diet. (2013)
    2. Parker AG, et al. The effects of IQPLUS Focus on cognitive function, mood and endocrine response before and following acute exercise. J Int Soc Sports Nutr. (2011)
    3. Schreiber S, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci. (2000)
    4. Kato-Kataoka A, et al. Soybean-derived phosphatidylserine improves memory function of the elderly Japanese subjects with memory complaints. J Clin Biochem Nutr. (2010)
    5. Manor I, et al. The effect of phosphatidylserine containing Omega3 fatty-acids on attention-deficit hyperactivity disorder symptoms in children: a double-blind placebo-controlled trial, followed by an open-label extension. Eur Psychiatry. (2012)
    6. Vakhapova V, et al. Phosphatidylserine containing omega-3 fatty acids may improve memory abilities in non-demented elderly with memory complaints: a double-blind placebo-controlled trial. Dement Geriatr Cogn Disord. (2010)
    7. Baumeister J, et al. Influence of phosphatidylserine on cognitive performance and cortical activity after induced stress. Nutr Neurosci. (2008)
    8. Jorissen BL, et al. The influence of soy-derived phosphatidylserine on cognition in age-associated memory impairment. Nutr Neurosci. (2001)
    9. Kingsley MI, et al. Effects of phosphatidylserine on exercise capacity during cycling in active males. Med Sci Sports Exerc. (2006)
    10. Kingsley MI, et al. Phosphatidylserine supplementation and recovery following downhill running. Med Sci Sports Exerc. (2006)
    11. Engel RR, et al. Double-blind cross-over study of phosphatidylserine vs. placebo in patients with early dementia of the Alzheimer type. Eur Neuropsychopharmacol. (1992)
    12. Crook T, et al. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull. (1992)
    13. Monteleone P, et al. Blunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men. Eur J Clin Pharmacol. (1992)

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