As seen in:
The cheat sheet to better health, a better body, and a better life.
Discover the truth about supplements that will help you control blood sugar, sleep better, boost your brain power, and achieve other health goals to live a better life.
Stop wasting time and money. Find the supplements that work!
If you've found this page, then you're probably looking to find out the truth about supplements - which work, and which don't. You know that supplements can help, but you don't know who to trust. Everywhere you turn, you're overwhelmed with companies promising you the latest and the greatest.
For the past two and a half years, we've been trudging through thousands and thousands of peer-reviewed scientific studies so that we can thoroughly understand supplements. Having analyzed over 30,000 individual studies, we've come to learn what works (and what doesn't).
Now, before we go any further, it's important to note: we are NOT here to sell you supplements. We don't own a line of supplements that we will steer you towards.
Beyond that, we're not in cahoots with anyone that does. In fact, we make NO brand recommendations. We make NO product recommendations. All we do is make sense of scientific research on supplementation and nutrition.
We've been compiling this research for a long time, and our Supplement-Goals Reference Guide puts it all together in an easy-to-use manner. You simply look up whichever supplement (eg "Vitamin D") or health goal (eg "blood glucose") you're interested in, and you will instantly know which supplements work (and which don't). Our guide literally solves all your supplement confusion.
See what other health and fitness professionals have to say about our work:
Dr. Michael Lewis, MD, MPH, MBA, FACPM
“No person serious about their health should be without it”
I recently discovered Examine.com and now realize I found what I was missing in my clinical practice – the authoritative, unbiased, noncommercial reference for supplements. Examine.com simplifies the complex world of nutritional supplements into one easy-to-use guide that is constantly updated with the latest research. No healthcare provider or person serious about their health should be without it.
Alan Aragon, BSc, MSc Nutrition
“the most diligent and comprehensive resource for science-based supplement information”
Examine.com is the most diligent and comprehensive resource for science-based supplement information, bar none. I refer students and colleagues to the site regularly, and I use it myself.
Mark Young, Physique Coach, Lean Bodies Consulting
“my default reference when it comes to supplementation”
As I've become increasingly busy with work and family commitments, it has gotten harder for me to stay on top of the supplement research.
Fortunately, Examine.com and their new supplement guide have pulled together all of the latest data in a meaningful and quickly accessible way. Their guide has rapidly become my default reference when it comes to supplementation.
Dr Joanna McMillan, PhD
“an invaluable resource for my work”
As a science-trained nutritionist, my entire work must be evidence-based if we are not to be constantly swayed by hyped up marketing claims or people's theories. But keeping abreast of research in every area of nutrition is impossible. When this guide landed in my inbox I was stoked. It is now an invaluable resource for my work. I have at my fingertips the studies to date on a particular supplement, I can click through to read them and I can see in one glance the conclusions that can be drawn. For anyone using or advising on supplement use, I cannot recommend this guide highly enough.
So who are we? We're an independent organization, and we do not get paid to shill for supplements. We don't recommend brands, and we don't recommend products. Instead, we keep our heads down, make sense of all the scientific research being conducted, and make recommendations based on evidence. We let the research speak for itself, and it's how we've gained the respect of doctors and nutrition experts. Every day, over 15,000 people visit our site to learn more about supplementation and nutrition.
These are just a few of the reasons why we're proud to present a guide that's:
- 300+ Supplements. We cover everything from 5-HTP and Aloe Vera all the way to Whey Protein and Zinc. We even cover supplements you may not have heard of, from 1,3-Dimethylamylamine (also known as DMAA) to Valerian. If you can supplement it, we have it covered.
- 180+ Health Goals. You want to live a healthier life, and we will help you get there. Find out which supplements help you (and which hinder you) towards your goals.
- 2,555 human studies. We've excluded animal and petri-dish studies, and only list human studies. You can rely on them being applicable to you, not rats.
With easy to use tables, all you need to do is simply search and click on whatever supplement or health goal you're interested in. Instantly, find supplements that work.
Dr. Emma-Leigh Synnott, MBBS, BVsc
“Unbiased and meticulously put together,”
During my years of study in science and Medicine one of the first and most powerful messages elucidated is that you will never have all the answers. So as a consequence you rapidly discover how to go about finding those answers...
Years later I can honestly say that my go to evidence-based information source on supplements would have to be Examine.com. Unbiased and meticulously put together, Examine.com provides a clear and detailed resource for novices and professionals alike.
Tom Venuto, bestselling author
“a no-brainer must-have for your library”
With Examine.com’s supplement reference guide, never again will you need to worry about knowing whether the claims of the billion dollar supplement industry are true or false. You’ll have the truth right at your fingertips. Use this encyclopedic resource as your go-to-guide and you’ll never have to waste time searching google and wondering whether what you found is evidence or (biased) advertisement, you won’t have to waste your money or risk your health on personal trial and error, and you won’t even have to sort through the real research (pub med) because the guys at Examine have spent years doing it for you. Maybe the best part is that, finally the evidence-based trustworthy information we need is all in one place, and is smartly organized so you can find the answers you need in just minutes. Whether you’re a consumer or a fitness pro, this is a no-brainer must-have for your library.
Let's rewind a bit. The use of herbs and other nutraceuticals as health supplements go back to the origins of civilized man. While not using the scientific method itself, our ancestors were taking notes on what supplements seemed to have what effect. They were wrong at times, but there was reasoning behind their choices.
Until 1990, dietary supplements were tightly regulated by the FDA. In 1990, The Nutrition Labeling and Education Act was passed, which expanded dietary supplements, but still required FDA pre-approval. It was the Dietary Supplement Health and Education Act in 1994 that opened up everything.
This resulted in both good and bad developments.
On the good side, this spurred more research in supplementation.
On the bad side, supplements became awash in marketing hype. It became commonplace to misinterpret or misrepresent research for financial gain. What was a promising field became overwhelmed with marketing hyperbole. It became very hard to trust what worked and what didn't.
The Supplement-Goals Reference Guide lets you quickly identify supplements that can help in your journey towards optimal health. There is no website or book that covers supplements like we do.
Let's be honest - supplements are a billion dollar industry. It's an industry built on big promises, great packaging, and fantastic marketing. You can find supplement companies listed in public stock exchanges all over the world, some of them worth billions on their own!
Lets take glutamine for example, an amino acid that is sold as a muscle builder. But did you know that it only builds muscle tissue... in petri-dishes? Or for those with severe burns? And did you know that glutamine is big business, generating over $600,000,000 a year in business? For the average gym-goer, glutamine is useless.
Examples like the above is why we created this guide - so you can separate fact from fiction. We tell the truth, and that's why most supplement companies hate us. And we wont stop accumulating more information. Information that will be right at your fingertips via our Supplement-Goals Reference Guide. Information that will save you money.
How about something that does work?
Ever heard of berberine? Originally used in traditional Chinese medicine, it's an alkaloid extracted from a yellow herb. Doesn't sound too impressive eh?
But diabetics who've used berberine love berberine. And why? Because scientific studies on its effects on blood glucose levels found that it had a strong effect in reducing blood glucose levels. In fact, its strength is comparable to the prescription drug metformin!
This kind of powerful information is what you will find in the Supplement-Goals Reference Guide. Information that will help you unlock your health.
You may be wondering - how can supplement companies get away with all this marketing hyperbole?
Let's go back to our previous example of glutamine. It was found to be a potent muscle-builder... except all of that muscle-building happened in petri-dishes (our intestines sequester glutamine in our bodies, and thus very little actually gets to your muscles).
It's a great example on how animal testing and petri-dish testing, while extremely important in keeping science progressing, is abused by marketers looking to make a quick buck.
And that's why we focus only on studies that were performed with actual humans. While our main site has over 30,000 scientific studies, our Supplement-Goals Reference Guide has just over 2000 studies. These are clinical tests done with humans, analyzing and comparing the performance of specific supplementation against placebo controls.
This way, you can be safe knowing that our recommendations are applicable to you, not rats.
Our Supplement-Goals Reference Guide is full of information and factoids that will let you find supplements that work for you.
Within seconds you'll be browsing around, identifying health goals you want to improve, and finding supplements that will help you get there. With no buy links in our guide, you can trust that our recommendations are based on science, not on making a quick buck.
Here's a small sample of health goals you will find covered:
If you want to live a better life, the Supplement-Goals Reference Guide will get there. It will save you time and money as you achieve better health!
Eric Cressey, MA, CSCS
“I highly recommend it.”
The supplement industry can be tremendously confusing for a number of reasons. First, the margins are incredibly high - so there are a lot of unethical weasels with no scientific background making bold and unsubstantiated claims to separate you from your money. Second, it's a dynamic industry, as new products, brands, and research emerge every single day. Fortunately, the guys at Examine.com have streamlined the process of educating us all by providing an incredibly up-to-date resource on the supplements we encounter on a daily basis, as well as some of the more obscure ones that are out there that might 'stump' us. This is an excellent product not only because it's a completely research-backed, unbiased perspective without any financial conflicts of interest, but also because it's exhaustively thorough and well written. I highly recommend it.
Dr. Yoni Freedhoff, MD CCFP Dip ABBM
“a massive and helpful undertaking”
It’s insufficient to simply rely on belief, conjecture or internet advice to determine if supplements are right for you. Instead you need to rely on research. With Examine.com’s reference guide not only will you find their summary of the research, but also links to the original papers should you want to do your own due diligence. Truly a massive and helpful undertaking.
Dr. Hector Lopez, MD, CSCS, FAAPMR
“I can highly endorse it without reservation”
The Examine.com site and comprehensive reference guide are both fantastic achievements for which both Kurtis Frank and Sol Orwell should be commended. When it comes to unbiased and reliable, evidence-based information on dietary supplements, applied nutrition and a wide array of health goals, their online database and reference guide are second-to-none. There is literally no other site that I am aware of like it. Beyond the expansive, thorough and comprehensive nature of their reviews, it is well organized with good interpretations of the available data. It's easy to see how valuable this resource will continue to be to me and many of my colleagues. I can highly endorse it without reservation.
Dr. Jonathan Fass, PT, DPT, CSCS
“it's absolutely vital”
When you consider the enormous and alarming amount of misleading and sometimes dangerous information that can be found in the world of health, nutrition and fitness today, the work being performed at Examine.com isn't just impressive, informative or thorough: it's absolutely vital. Examine.com is more than just "another" source of information: in my opinion, it is *the* source, with easily understood breakdowns of complex concepts and research, informative topics and information that can be used *right now* to improve your health, your performance and your life. Examine.com is like a GPS system for navigating the suspect claims of lesser sources and arriving at the most important destination of them all: the Truth
NOTE: The Supplement-Goals Reference Guide is a downloadable eBook in PDF format. Once you buy, you get instant lifetime access.
Every day, at 5am EST, our internal systems extract data from the complete Examine.com database (which features over 30,000 scientific studies) to obtain the relevant human data and re-create The Supplement-Goals Reference Guide.
The benefit of a downloadable PDF is that you get all these daily updates for FREE. This is the main benefit of eBooks - your purchase is like a lifetime membership, giving you access to the latest supplementation research.
The Supplement-Goals Reference Guide allows you to unlock the power of supplements and their effects on your health.
All in 30 seconds or less.
And If you have clients who look up to you, the Supplement-Goals Reference is a must for you.
Coaches, nutrionists, naturopaths, teachers, and more - your clients will be amazed by your ability to deconstruct any supplement or any health goal and instantly know what works and what doesn't. You'll even be able to cite real human studies as proof.
This is as close to a supplement magic trick as you can get, except there's no magic - just thousands of hours of real research by us. Research that will make make you look like a wizard.
You'll notice that we are not offering free bonuses, special reports, or anything else written by us or even random authors you've never heard of before. There's a simple reason - you don't need that junk.
We firmly believe that the Supplement-Goals Reference Guide is a vital resource. We don't need to entice you with extra perks or other marketing techniques.
We're putting our names on the line, and that's because we're confident that not only will you find it extremely useful, there's nothing else like this out there. There's a reason why we are the most respected name in supplementation and nutrition.
We guarantee that you will find the Supplements-Goals Reference Guide useful over the next 30 days. If for some reason you want a refund, simply tell us and we will send you a prompt refund, no questions asked.
|Kurtis Frank||Dr. Spencer Nadolsky|
“the encyclopedia on supplements”
Instead of writing a testimonial for Examine's reference TOME, I've copied my exact response to Sol about an hour after he sent me a preliminary copy of it:
This is seriously legit. You just wrote the encyclopedia on supplements. I don't know if I've ever come across reference material as valuable as this.
So yeah: It's good--really really good--like, holy shit somebody actually pulled this off, good.
Shawn Myszka, MS, CSCS*D, PES
“I have never seen a resource as comprehensive and unbiased”
All it took was one look at Examine.com’s Supplement Guide and I was unequivocally sold. I have never seen a resource as comprehensive and unbiased as this especially for the often misunderstood world of dietary supplements. Being a former National-level competitive bodybuilder and now serving as a personal development coach/consultant for players in the NFL, the guide contains information that people in our industry used to have to rely on anecdotal evidence with but now have proven answers at our fingertips. The guide truly goes above and beyond to raise the bar in a nearly untouchable way. I highly recommend it to anyone who takes their performance, health, and fitness goals seriously.
Dr. Bojan Kostevski, MD
“helps me save both time and money”
For me, the Supplement-Goals Reference comes as a relief as I often need to find a quick reference to a supplement but, being a busy guy, can't always afford spending time looking for the papers explaining it's effect and limitations. I have nothing but trust for the staff running examine.com and consider this to be a trusted source of unbiased and accurate information for not only finding the effect of, but also understanding limitations in the research conducted in the most common supplements. The reference guide helps me save both time and money (and sanity) since I can quickly asses and answer my patients' and clients' questions when it comes to supplements where I'm not 100% up to date with current research. Much recommended for anyone interested in the hard fact about supplements without having to spend hours looking for the references in scientific literature.
Nadine Shaban, MSc HK, BM, PICP
“Straight talk about supplements”
Research driven, evidence based and over 20000+ citations. Being a health practitioner and fitness lover they bring research and supplementation to the next level. Quick, succinct reads. Straight talk about specific supplements and gives us the direct facts. I will be recommending this site to all my clients and friends so they can learn about what they are taking, and what benefits (if any) they are getting from supplements. There is no other site like this.
Dr. Grainne Murphy, MB BCh BAO, MMedSci
“It’s the ultimate supplement bible”
When I first visited Examine.com, I was angry. It's one of those things that made me kick myself. Why didn't I think of that? It's something that was so badly needed. The supplement industry is huge and full of anecdotes and testimonials but very little science. The reason I’m not behind Examine, of course, is that I learned in my medical training just how difficult it is to do literature reviews, and particularly to do them well. It's time consuming, tedious and difficult. The guys at Examine have done all the hard work for you. It's pretty much an essential resource if you're even contemplating supplementation. You think Big Pharma is out to get you? The drug companies have nothing on the supplement guys with their shiny boxes and lightning bolts full of promises.
I recommend Examine.com because I’m a fan of science and evidence based medicine. Because I'm too lazy to trawl through all the relevant papers myself. And because I don't want to waste money or risk my health on things that don't even work or might harm me. Sol and Kurtis have spent endless hours reviewing thousands and thousands of papers to come up with the hard facts and put them all in one easily accessible place. I think everybody owes it to themselves to invest some time in Examine and the guide. It’s the ultimate supplement bible.
Mike Matthews, bestselling author
“If you want to know the truth about on supplementation and nutrition ...”
When I need to do supplement or nutrition research, Examine.com is the first website I open. Their database is absolutely massive, their Human Effect Matrixes are invaluable, and their summaries of how the substances work in the body are thorough and unbiased.
If you want to know the truth about how supplementation and nutrition choices affect the body, you need to dive into Examine.com and their Supplement-Goals Reference Guide.
James S. Fell, nationally syndicated columnist
“dispel hype, destroy myths”
You know what I love about Examine.com? I love that they do not care about the outcome of their research. These guys are unbiased, and only seek the truth when researching supplements. They dispel hype, destroy myths, and share the fruits of their ethical curiosity to find out what works, how well it works, and why. If you're thinking about taking any type of supplement, make sure you check it on Examine.com first for unbiased reporting.
Dr. Jose Antonio, PhD. Co-founder, ISSN
“Plenty of real science, no bro-science”
Examine.com rocks! It's a great source of information on the science of dietary supplements. Plenty of real science, no bro-science. It's the real deal. Kudos to Sol Orwell and Kurtis Frank for showing the rest of the nutrition world that indeed, there's plenty of science in the field of dietary supplements. Pass me the creatine please! :-)
When you dive into the pages of our Supplements-Goals Reference Guide, brace yourself.
Clocking in at over 900 pages and over 2000 human studies, it's a lot of information.
Don't try to read it all at once. Look up a supplement you're interested in (everyone's talking about Vitamin D right now). Or look up a health goal you want to optimize (see which supplements help decrease anxiety).
Once you get the hang of it, be prepared to be blown away. We promise you won't be confused by supplements again.
Q: Is this a one-time fee or do I pay every month?
One time. This isn't one of those recurring scams the other guys run. You pay us once, you get lifetime access. As long as we're updating Examine.com, you have the latest information at your fingertips.
Q: Does this come in a physical book?
At almost 800 pages, a physical copy of the Supplement-Goals Reference Guide would be big. The PDF lets you quickly and easily access supplement information wherever you are. Even without Internet-access.
Q: How does this differ from the main website?
Three big reasons: