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The cheat sheet to better health, a better body, and a better life.

No bro-science.
It's the real deal.
Dr. Jose Antonio, PhD, International Society of Sports Nutrition

Discover the truth about supplements that will help you control blood sugar, sleep better, boost your brain power, and achieve other health goals to live a better life.

Stop wasting time and money. Find the supplements that work!

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If you've found this page, then you're probably looking to find out the truth about supplements - which work, and which don't. You know that supplements can help, but you don't know who to trust. Everywhere you turn, you're overwhelmed with companies promising you the latest and the greatest.

For the past two and a half years, we've been trudging through thousands and thousands of peer-reviewed scientific studies so that we can thoroughly understand supplements. Having analyzed over 36,000 individual studies, we've come to learn what works (and what doesn't).

Now, before we go any further, it's important to note: we are NOT here to sell you supplements. We don't own a line of supplements that we will steer you towards.

Beyond that, we're not in cahoots with anyone that does. In fact, we make NO brand recommendations. We make NO product recommendations. All we do is make sense of scientific research on supplementation and nutrition.

We've been compiling this research for a long time, and our Supplement-Goals Reference Guide puts it all together in an easy-to-use manner. You simply look up whichever supplement (eg "Vitamin D") or health goal (eg "blood glucose") you're interested in, and you will instantly know which supplements work (and which don't). Our guide literally solves all your supplement confusion.

See what other health and fitness professionals have to say about our work:

Dr. Spencer Nadolsky
it's the best

I have used Natural Standard in the past which costs 400 dollars per year. I have since switched to for my supplement information as it's the best.

Eric Cressey, MA, CSCS
I highly recommend it.

The supplement industry can be tremendously confusing for a number of reasons. First, the margins are incredibly high - so there are a lot of unethical weasels with no scientific background making bold and unsubstantiated claims to separate you from your money. Second, it's a dynamic industry, as new products, brands, and research emerge every single day. Fortunately, the guys at have streamlined the process of educating us all by providing an incredibly up-to-date resource on the supplements we encounter on a daily basis, as well as some of the more obscure ones that are out there that might 'stump' us. This is an excellent product not only because it's a completely research-backed, unbiased perspective without any financial conflicts of interest, but also because it's exhaustively thorough and well written. I highly recommend it.

Dr. Jose Antonio, PhD. Co-founder, ISSN
Plenty of real science, no bro-science rocks! It's a great source of information on the science of dietary supplements. Plenty of real science, no bro-science. It's the real deal. Kudos to Sol Orwell and Kurtis Frank for showing the rest of the nutrition world that indeed, there's plenty of science in the field of dietary supplements. Pass me the creatine please! :-)

Dr. Emma-Leigh Synnott, MBBS, BVsc
Unbiased and meticulously put together,

During my years of study in science and Medicine one of the first and most powerful messages elucidated is that you will never have all the answers. So as a consequence you rapidly discover how to go about finding those answers...

Years later I can honestly say that my go to evidence-based information source on supplements would have to be Unbiased and meticulously put together, provides a clear and detailed resource for novices and professionals alike.

So who are we? We're an independent organization, and we do not get paid to shill for supplements. We don't recommend brands, and we don't recommend products. Instead, we keep our heads down, make sense of all the scientific research being conducted, and make recommendations based on evidence. We let the research speak for itself, and it's how we've gained the respect of doctors and nutrition experts. Every day, over 15,000 people visit our site to learn more about supplementation and nutrition.

These are just a few of the reasons why we're proud to present a guide that's:

  • Simple and easy to use. Look up any supplement or health goal, and instantly know what works (and what doesn't).
  • Neutral & Independent. We don't recommend any brand or any specific product, and we make no money on any purchases you make.
  • Comprehensive. You won't need to use any other resource. We have the references to prove what we say.
  • Transparent. Every single one of our conclusions links directly to the corresponding scientific papers. For those that want more information, we even breakdown the demographics, the conclusions, and notes on every single paper we've reviewed.

  • 300+ Supplements. We cover everything from 5-HTP and Aloe Vera all the way to Whey Protein and Zinc. We even cover supplements you may not have heard of, from 1,3-Dimethylamylamine (also known as DMAA) to Valerian. If you can supplement it, we have it covered.
  • 180+ Health Goals. You want to live a healthier life, and we will help you get there. Find out which supplements help you (and which hinder you) towards your goals.
  • 2,668 human studies. We've excluded animal and petri-dish studies, and only list human studies. You can rely on them being applicable to you, not rats.

With easy to use tables, all you need to do is simply search and click on whatever supplement or health goal you're interested in. Instantly, find supplements that work.

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Tom Venuto, bestselling author
a no-brainer must-have for your library

With’s supplement reference guide, never again will you need to worry about knowing whether the claims of the billion dollar supplement industry are true or false. You’ll have the truth right at your fingertips. Use this encyclopedic resource as your go-to-guide and you’ll never have to waste time searching google and wondering whether what you found is evidence or (biased) advertisement, you won’t have to waste your money or risk your health on personal trial and error, and you won’t even have to sort through the real research (pub med) because the guys at Examine have spent years doing it for you. Maybe the best part is that, finally the evidence-based trustworthy information we need is all in one place, and is smartly organized so you can find the answers you need in just minutes. Whether you’re a consumer or a fitness pro, this is a no-brainer must-have for your library.

Stephan J. Guyenet, PhD
refreshingly free of bias provides thorough, good quality information on a variety of supplements and other nutrition/health topics. It is refreshingly free of ideological bias.

Let's rewind a bit. The use of herbs and other nutraceuticals as health supplements go back to the origins of civilized man. While not using the scientific method itself, our ancestors were taking notes on what supplements seemed to have what effect. They were wrong at times, but there was reasoning behind their choices.

Until 1990, dietary supplements were tightly regulated by the FDA. In 1990, The Nutrition Labeling and Education Act was passed, which expanded dietary supplements, but still required FDA pre-approval. It was the Dietary Supplement Health and Education Act in 1994 that opened up everything.

This resulted in both good and bad developments.

On the good side, this spurred more research in supplementation.

On the bad side, supplements became awash in marketing hype. It became commonplace to misinterpret or misrepresent research for financial gain. What was a promising field became overwhelmed with marketing hyperbole. It became very hard to trust what worked and what didn't.

The Supplement-Goals Reference Guide lets you quickly identify supplements that can help in your journey towards optimal health. There is no website or book that covers supplements like we do.

Let's be honest - supplements are a billion dollar industry. It's an industry built on big promises, great packaging, and fantastic marketing. You can find supplement companies listed in public stock exchanges all over the world, some of them worth billions on their own!

Lets take glutamine for example, an amino acid that is sold as a muscle builder. But did you know that it only builds muscle tissue... in petri-dishes? Or for those with severe burns? And did you know that glutamine is big business, generating over $600,000,000 a year in business? For the average gym-goer, glutamine is useless.

Examples like the above is why we created this guide - so you can separate fact from fiction. We tell the truth, and that's why most supplement companies hate us. And we wont stop accumulating more information. Information that will be right at your fingertips via our Supplement-Goals Reference Guide. Information that will save you money.

How about something that does work?

Ever heard of berberine? Originally used in traditional Chinese medicine, it's an alkaloid extracted from a yellow herb. Doesn't sound too impressive eh?

But diabetics who've used berberine love berberine. And why? Because scientific studies on its effects on blood glucose levels found that it had a strong effect in reducing blood glucose levels. In fact, its strength is comparable to the prescription drug metformin!

This kind of powerful information is what you will find in the Supplement-Goals Reference Guide. Information that will help you unlock your health.

You may be wondering - how can supplement companies get away with all this marketing hyperbole?

Let's go back to our previous example of glutamine. It was found to be a potent muscle-builder... except all of that muscle-building happened in petri-dishes (our intestines sequester glutamine in our bodies, and thus very little actually gets to your muscles).

It's a great example on how animal testing and petri-dish testing, while extremely important in keeping science progressing, is abused by marketers looking to make a quick buck.

And that's why we focus only on studies that were performed with actual humans. While our main site has over 36,000 scientific studies, our Supplement-Goals Reference Guide has just over 2000 studies. These are clinical tests done with humans, analyzing and comparing the performance of specific supplementation against placebo controls.

This way, you can be safe knowing that our recommendations are applicable to you, not rats.

Our Supplement-Goals Reference Guide is full of information and factoids that will let you find supplements that work for you.

Within seconds you'll be browsing around, identifying health goals you want to improve, and finding supplements that will help you get there. With no buy links in our guide, you can trust that our recommendations are based on science, not on making a quick buck.

Here's a small sample of health goals you will find covered:

  • Anxiety
  • Allergies
  • Appetite
  • Asthma
  • Attention
  • Blood pressure
  • Breast tenderness
  • Depression
  • Erections
  • Estrogen
  • Fertility
  • Glycemical control
  • Hair regrowth
  • Immunity
  • Inflammation
  • Insomnia
  • Kidney function
  • Memory
  • Nausea
  • Pain
  • Protection from Smoking
  • Skin quality
  • Stress
  • Uric acid

The actual reference has over 180 different health goals listed!

If you want to live a better life, the Supplement-Goals Reference Guide will get there. It will save you time and money as you achieve better health!

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Alan Aragon, BSc, MSc Nutrition
the most diligent and comprehensive resource for science-based supplement information is the most diligent and comprehensive resource for science-based supplement information, bar none. I refer students and colleagues to the site regularly, and I use it myself.

Mark Young, Physique Coach, Lean Bodies Consulting
my default reference when it comes to supplementation

As I've become increasingly busy with work and family commitments, it has gotten harder for me to stay on top of the supplement research.

Fortunately, and their new supplement guide have pulled together all of the latest data in a meaningful and quickly accessible way. Their guide has rapidly become my default reference when it comes to supplementation.

Dr Joanna McMillan, PhD
an invaluable resource for my work

As a science-trained nutritionist, my entire work must be evidence-based if we are not to be constantly swayed by hyped up marketing claims or people's theories. But keeping abreast of research in every area of nutrition is impossible. When this guide landed in my inbox I was stoked. It is now an invaluable resource for my work. I have at my fingertips the studies to date on a particular supplement, I can click through to read them and I can see in one glance the conclusions that can be drawn. For anyone using or advising on supplement use, I cannot recommend this guide highly enough.

Dr. Michael Lewis, MD, MPH, MBA, FACPM
No person serious about their health should be without it

I recently discovered and now realize I found what I was missing in my clinical practice – the authoritative, unbiased, noncommercial reference for supplements. simplifies the complex world of nutritional supplements into one easy-to-use guide that is constantly updated with the latest research. No healthcare provider or person serious about their health should be without it.

NOTE: The Supplement-Goals Reference Guide is a downloadable eBook in PDF format. Once you buy, you get instant lifetime access.

Every day, at 5am EST, our internal systems extract data from the complete database (which features over 36,000 scientific studies) to obtain the relevant human data and re-create The Supplement-Goals Reference Guide.

The benefit of a downloadable PDF is that you get all these daily updates for FREE. This is the main benefit of eBooks - your purchase is like a lifetime membership, giving you access to the latest supplementation research.

The Supplement-Goals Reference Guide allows you to unlock the power of supplements and their effects on your health.

All in 30 seconds or less.

And If you have clients who look up to you, the Supplement-Goals Reference is a must for you.

Coaches, nutrionists, naturopaths, teachers, and more - your clients will be amazed by your ability to deconstruct any supplement or any health goal and instantly know what works and what doesn't. You'll even be able to cite real human studies as proof.

This is as close to a supplement magic trick as you can get, except there's no magic - just thousands of hours of real research by us. Research that will make make you look like a wizard.

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You'll notice that we are not offering free bonuses, special reports, or anything else written by us or even random authors you've never heard of before. There's a simple reason - you don't need that junk.

We firmly believe that the Supplement-Goals Reference Guide is a vital resource. We don't need to entice you with extra perks or other marketing techniques.

We're putting our names on the line, and that's because we're confident that not only will you find it extremely useful, there's nothing else like this out there. There's a reason why we are the most respected name in supplementation and nutrition.

We guarantee that you will find the Supplements-Goals Reference Guide useful over the next 30 days. If for some reason you want a refund, simply tell us and we will send you a prompt refund, no questions asked.


Kurtis Frank Dr. Spencer Nadolsky

Get The Supplement-Goals Reference Guide today and find supplements to improve your health within 24 hours. Don't waste your money on useless supplements.

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Laurent Bannock, MSc, CISSN, CSCS
an essential tool in my toolbox as a nutritionist & lecturer

For an objective evidenced based resource on supplements I HIGHLY Recommend 'The Supplement Goals Reference Guide'. Ever since getting a copy, I now consider an essential tool in my toolbox as a practising performance nutritionist & lecturer.

Mike T Nelson, PhD, MSME, CSCS
You can either spend years trying to figure it out on your own, or just flip to the correct section

These guys put out a reference guide that is my go to source for unbiased supplement research. It is complete with the actual references and in an easy to use format. Excellent work guys on a job well done. You can either spend years trying to figure it out on your own, or just flip to the correct section. Highly recommended.

Alex Ferentinos, Nutrition and Training Consultant
The absolute definitive one stop shop is an invaluable resource. In an age of unfounded claims and overhyped results it can be hard to find solid information. The guys have spent years looking into the research across a vast range of sports supplementation to let you know what each one may and may not do, free of hype and commercial bias with sound understanding of solid research methods. The absolute definitive one stop shop.

Jon-Erik Kawamoto, CSCS, CEP
my go-to resource for supplements and nutrition is my go-to resource for supplements and nutrition. There is a lot of fluff out there in the industry about nutrition and what supplements to take, but the people behind have put in the pain-staking time to back up or debunk these claims with science. It's hard to know what to believe and what to ignore, so when I want to read the latest research, I go to

McKel Hill, MS, RD, LDN Registered Dietitian
it's a MUST HAVE in my resources! has been a personal resource of mine for years purely for the fact that they have one mission, to deliver un-biased evidenced based scientific data and research on a wide variety of common dietary supplements (in over 20,000 articles). The Supplement Goals Reference Guide is one of the most, if not the most, comprehensive guides I've seen on dietary supplements/nutrition. It's incredibly user friendly, factual, and straight to the point. I highly recommend this guide to my clients and other health care professionals, it's a MUST HAVE in my resources!

Dean Somerset, BSc. Kinesiology, CEP, CSCS, MEPD
an amazing job of sifting through thousands of research articles

The guys at are leading the way in weeding out the facts from the fallacies in terms of nutritional science and application. There's a reason I've had them do multiple guest posts on my site, and a bigger reason why they're some of the most highly shared and clicked on articles on my site. They do an amazing job of sifting through hundreds if not thousands of research articles and finding commonalities and divergences among them in order to give you the most up to date and comprehensive information possible. If you've ever been confused about what research tells you about nutrition and supplementation, look no further than these two and

Aidan Goggins, B Pharm MSc Nutr Med, Author of The Health Delusion
an invaluable resource

The way we approach health is rapidly changing; the public demands both a greater say in their treatment and the option to utilise proven nutritional therapies. offers an invaluable resource for achieving this, providing clear and well researched information that empowers the user, allowing an equal discourse between them and their healthcare provider.

Paul Ingraham
one of the few websites I trust for detailed, current, and science-based analysis

In a world full of blogs, is a breath of fresh air: designed as a deep resource and a useful tool, it is one of the few websites I trust for detailed, current, and science-based analysis. If I need to know anything about supplementation science or best practices, is my first stop, and often the only one I need.

When you dive into the pages of our Supplements-Goals Reference Guide, brace yourself.

Clocking in at over 900 pages and over 2000 human studies, it's a lot of information.

Don't try to read it all at once. Look up a supplement you're interested in (everyone's talking about Vitamin D right now). Or look up a health goal you want to optimize (see which supplements help decrease anxiety).

Once you get the hang of it, be prepared to be blown away. We promise you won't be confused by supplements again.

Q: Is this a one-time fee or do I pay every month?

One time. This isn't one of those recurring scams the other guys run. You pay us once, you get lifetime access. As long as we're updating, you have the latest information at your fingertips.

Q: Does this come in a physical book?

At almost 800 pages, a physical copy of the Supplement-Goals Reference Guide would be big. The PDF lets you quickly and easily access supplement information wherever you are. Even without Internet-access.

Q: How does this differ from the main website?

Three big reasons:

  1. It's extremely easy to use. Everything is there, right at your fingertips. Search, find what you're looking for, and done. It will take you less than 5 seconds.
  2. It's offline. No matter where you are - in a classroom, in a store, wherever - you have the information available to you.
  3. It helps you unlock Health Goals. This is big. The website only focuses on Supplements and what their Health Goals are. The Supplement-Goals Reference Guide lets you find supplements based on your health goals. Utilize supplementation for better health, a better body, and a better life!

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