Improving Insulin Sensitivity

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Information

The supplements listed here are those that, unless otherwise specified, have been shown to improve insulin sensitivity in humans and work somewhat directly (ie. Ephedrine increasing insulin sensitivity secondary to fat loss would not be listed, since it was actually the fat loss improving insulin sensitivity)

Some studies that have been conducted in lab animals but deserve notable mention may also be mentioned; these supplements will be specified



Suggested Supplements

Dosage: 2g

L-Carnitine has 4 studies, 3 of which show improvement in insulin sensitivity. These studies have been conducted with twice daily dosages with either L-Carnitine or Acetyl-L-Carnitine (should also apply to the forms of LCLT and GPLC) and are in persons with impaired glucose metabolism.

No evidence currently exists for otherwise healthy people, and one of the studies noting more significance with a further worsening profile (and thus less effects from a better profile) imply that L-Carnitine may not benefit healthy person's insulin sensitivity.



Dosage: 3-500

The studies conducted have used a wide variety of doses, and insulin improvements have been seen in Type II diabetics (3mg) insulin impaired obese persons without diabetes (150mg) and in normal persons (1, 1.5, 2g). One study using 100mg in obese persons failed to note benefits.

It appears low doses can help those with poor insulin control, with progressively higher doses being needed as insulin control is closer to the 'ideal' range.



Dosage: 1g

The only study showing benefits was conducted in type II diabetics using 1g of the seed extract, consumed via food products. It did, however, note benefit; this is in accordance with traditional usage of fenugreek seeds to counter diabetes in Ayurvedic medicine.

This is not 1g of a concentrated extract (usually standardized to fenusides); the fenusides may not be the active component here and thus a non-concentrated extract would be desirable.



Dosage: 1,750

TUDCA was shown in one study to increase insulin sensitivity in men over 4 weeks, but it appeared to benefit only muscle tissue and the liver; preliminary evidence, but promising.

The improvement in insulin sensitivity was independent of fat loss.



Dosage: 800

A large dose of GTCs was able to improve insulin sensitivity acutely in otherwise healthy young men with no abnormal glucose metabolism; this may be through glucose deposition (getting glucose out of the blood stream)

In studies looking at long term usage of green tea and insulin sensitivity, only the high doses (800mg or more) appear to have worked. Minimal studies though.



Dosage: 900

300mg taken three times a day with meal (900mg total) in diabetic persons or persons with impaired insulin sensitivity appears to be effective in improving insulin sensitivity alongside other parameters of diabetes (insulin concentration, fasting and postprandial glucose, HbA1c)



Tags

insulin, sensitivity, glucose, control, resistance, diabetes


IMPORTANT NOTICE: The stack pages are not being updated and have been kept for archival purposes.

Due to the extreme complexity of stacking with proper consideration to demographics such as age, requirements, and gender, we have released a far more encompassing fit - The Stack Guides

With FREE lifetime updates and authored by over a dozen researchers, it is the clearest guide to supplementation there is.

Must Get!

Saving You Money & Time!

Supplement Stack Guides