Anti-Estrogen

IMPORTANT NOTICE: The stack pages are not being updated and have been kept for archival purposes.

Due to the extreme complexity of stacking with proper consideration to demographics such as age, requirements, and gender, we have released a far more encompassing fit - The Stack Guides

With FREE lifetime updates and authored by over a dozen researchers, it is the clearest guide to supplementation there is.

Must Get!

Saving You Money & Time!

Supplement Stack Guides

Examine.com is:

  • 100% Independent - no ties to any supplement company

  • Unbiased - we do not sell any supplements

  • Neutral - we have researchers from a wide array of backgrounds

  • Trusted - have been published in mainstream media and peer-review


Information

This page includes supplements that are either aromatase inhibitors (by inhibiting the enzyme that converts testosterone to estrogen, a relative deficiency of estrogen occurs) or otherwise reduce the effects of estrogen on the level of the receptor.



Suggested Supplements

Dosage: 25mg

NOT DHEA per se, but the metabolite known as Androsta-3,5-diene-7,17-dione. This metabolite appears to have very potent anti-aromatase properties in vitro and is currently being sold as a nutraceutical with promising anecdotes. DHEA itself may be estrogenic (and the 7-oxo metabolite neither pro nor anti-estrogenic)

No direct human studies currently, but 25mg thrice a day (75mg total) has been used.



Dosage: 2g

2g of Grape Seed Extract (GSE) appears to be the human equivalent of the animal studies that noted in vivo aromatase inhibition. The large oral dose is because of the poor bioavailability and absorption of the procyanidins in GSE, and although the benefits seen with lower doses are benefits shared with catechins (what the procyanidins degrade into) the catechins are inactive on aromatase.



Dosage: 200

200mg is the basic dosage of Eurycoma that is used, the actual dose for anti-estrogenic effects is less known. Anti-estrogenic effects have been noted in rats and thought to be due to the eurycomanone compound, and the dose required in rats after considering subpar bioavailability (9.48mg) in a human dose (1.51mg) and assuming the standard 1.6% eurycomanone content of basic Eurycoma Longifolia extract, the 200mg extract appears to be more than enough.

No actual human interventions into Eurycoma Longifolia have been conducted.



Tags

anti, estrogen, reduce, against, lower


IMPORTANT NOTICE: The stack pages are not being updated and have been kept for archival purposes.

Due to the extreme complexity of stacking with proper consideration to demographics such as age, requirements, and gender, we have released a far more encompassing fit - The Stack Guides

With FREE lifetime updates and authored by over a dozen researchers, it is the clearest guide to supplementation there is.

Must Get!

Saving You Money & Time!

Supplement Stack Guides