Platelet Aggregation

    Last Updated: April 29, 2017

    Platelet aggregation is the rate of which platelets in the blood can form clots to stop bleeding. While it serves a vital role in preventing excessive bleeding, abnormally active aggregation can be a risk factor for cardiovascular diseases.

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    Examine Database: Platelet Aggregation

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    Examine Database References

    1. Vitamin E - Clarke MW, Ward NC, Wu JH, Hodgson JM, Puddey IB, Croft KDSupplementation with mixed tocopherols increases serum and blood cell gamma-tocopherol but does not alter biomarkers of platelet activation in subjects with type 2 diabetesAm J Clin Nutr.(2006 Jan)
    2. Vitamin E - Singh I, Turner AH, Sinclair AJ, Li D, Hawley JAEffects of gamma-tocopherol supplementation on thrombotic risk factorsAsia Pac J Clin Nutr.(2007)
    3. Fish Oil - L Axelrod, J Camuso, E Williams, K Kleinman, E Briones, D SchoenfeldEffects of a Small Quantity of omega-3 Fatty Acids on Cardiovascular Risk Factors in NIDDM. A Randomized, Prospective, Double-Blind, Controlled StudyDiabetes Care.(1994 Jan)
    4. Cocoa Extract - Carnevale R, Loffredo L, Pignatelli P, Nocella C, Bartimoccia S, Di Santo S, Martino F, Catasca E, Perri L, Violi FDark chocolate inhibits platelet isoprostanes via NOX2 down-regulation in smokersJ Thromb Haemost.(2012 Jan)
    5. Sea Buckthorn - Johansson AK, Korte H, Yang B, Stanley JC, Kallio HPSea buckthorn berry oil inhibits platelet aggregationJ Nutr Biochem.(2000 Oct)
    6. Garlic - Scharbert G, Kalb ML, Duris M, Marschalek C, Kozek-Langenecker SAGarlic at dietary doses does not impair platelet functionAnesth Analg.(2007 Nov)
    7. Fish Oil - Mackay I, Ford I, Thies F, Fielding S, Bachoo P, Brittenden JEffect of Omega-3 fatty acid supplementation on markers of platelet and endothelial function in patients with peripheral arterial diseaseAtherosclerosis.(2012 Jan 13)
    8. Fish Oil - Serebruany VL, Miller M, Pokov AN, Lynch D, Jensen JK, Hallén J, Atar DEarly impact of prescription Omega-3 fatty acids on platelet biomarkers in patients with coronary artery disease and hypertriglyceridemiaCardiology.(2011)
    9. Cocoa Extract - Luisa M Ostertag, Paul A Kroon, Sharon Wood, Graham W Horgan, Elena Cienfuegos-Jovellanos, Shikha Saha, Garry G Duthie, Baukje de RoosFlavan-3-ol-enriched dark chocolate and white chocolate improve acute measures of platelet function in a gender-specific way--a randomized-controlled human intervention trialMol Nutr Food Res.(2013 Feb)
    10. Grape Juice - Albers AR, Varghese S, Vitseva O, Vita JA, Freedman JEThe antiinflammatory effects of purple grape juice consumption in subjects with stable coronary artery diseaseArterioscler Thromb Vasc Biol.(2004 Nov)
    11. Fish Oil - Hendra TJ, Britton ME, Roper DR, Wagaine-Twabwe D, Jeremy JY, Dandona P, Haines AP, Yudkin JSEffects of fish oil supplements in NIDDM subjects. Controlled studyDiabetes Care.(1990 Aug)
    12. Cocoa Extract - Pearson DA, Paglieroni TG, Rein D, Wun T, Schramm DD, Wang JF, Holt RR, Gosselin R, Schmitz HH, Keen CLThe effects of flavanol-rich cocoa and aspirin on ex vivo platelet functionThromb Res.(2002 May 15)
    13. Garlic - K Rahman, D BillingtonDietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humansJ Nutr.(2000 Nov)
    14. Grape Juice - Keevil JG, Osman HE, Reed JD, Folts JDGrape juice, but not orange juice or grapefruit juice, inhibits human platelet aggregationJ Nutr.(2000 Jan)
    15. Garlic - Steiner M, Li WAged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functionsJ Nutr.(2001 Mar)
    16. Cocoa Extract - Ottaviani JI, Balz M, Kimball J, Ensunsa JL, Fong R, Momma TY, Kwik-Uribe C, Schroeter H, Keen CLSafety and efficacy of cocoa flavanol intake in healthy adults: a randomized, controlled, double-masked trialAm J Clin Nutr.(2015 Dec)
    17. Garlic - Steiner M, Lin RSChanges in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extractJ Cardiovasc Pharmacol.(1998 Jun)
    18. Cocoa Extract - Hamed MS, Gambert S, Bliden KP, Bailon O, Singla A, Antonino MJ, Hamed F, Tantry US, Gurbel PADark chocolate effect on platelet activity, C-reactive protein and lipid profile: a pilot studySouth Med J.(2008 Dec)